منابع مشابه
Woodchuck Hepatitis Virus Post-Transcriptional Regulation Element (WPRE) Promotes Anti-CD19 BiTE Expression in Expi293 Cells
Background: Bispecific antibodies represent an important class of mAbs, with great therapeutic potentials due to their ability to target simultaneously two distinct epitopes. The generation of functional bispecific antibodies with the highest possible yields is particularly critical for the production of these compounds on industrial scales. Anti- CD3 × CD19 bsAb is a bispecific T-cell engager ...
متن کاملQuick change: post-transcriptional regulation in Pseudomonas
Pseudomonas species have evolved dynamic and intricate regulatory networks to fine-tune gene expression, with complex regulation occurring at every stage in the processing of genetic information. This approach enables Pseudomonas to generate precise individual responses to the environment in order to improve their fitness and resource economy. The weak correlations we observe between RNA and pr...
متن کاملPost-transcriptional gene regulation in chondrocytes.
The control of gene expression in articular chondrocytes is an essential factor in maintaining the homoeostasis of extracellular matrix synthesis and turnover necessary in healthy articular cartilage. Although much is known of how steady-state levels of gene expression and rates of transcription are altered, there has been a poorer understanding of gene control at the post-transcriptional level...
متن کاملPost-transcriptional gene regulation in mature neurons
OF THE DISSERTATION ........................................................................... ii DEDICATION .................................................................................................................... v LIST OF FIGURES AND TABLES.................................................................................. ix ACKNOWLEDGMENTS ...........................................
متن کاملPost-Transcriptional Regulation of Papillomavirus Gene Expression
Papillomavirus genomes are transcribed as one large complex transcription unit with multiple promoters, two poly(A) sites (early and late), and considerable alternative splicing. As a result, there are multiple opportunities for post-transcriptional regulation of papillomavirus gene expression. Although this area has not been as extensively studied as transcriptional regulation, there are a few...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biology of the Cell
سال: 2004
ISSN: 0248-4900
DOI: 10.1016/j.biolcel.2004.05.002